Why Dr. McCullough Talks About Nattokinase

Nattokinase is an enzyme from natto, a fermented soybean dish that’s been eaten in Japan for over a thousand years. Among independent doctors, few people have talked about it more than Dr. Peter McCullough.

In his own words

“Out of all the available therapies I have used in my practice and among all the proposed detoxification agents, I believe nattokinase and related peptides hold the greatest promise for patients at this time.” (The Focal Points, Feb 2023)

On dosing, he wrote:

“Thus an empiric starting dose could be 2000 FU twice a day. Full pharmacokinetic and pharmacodynamic studies have not been completed, but several years of market use as an over-the-counter supplement suggests nattokinase is safe with the main caveat being excessive bleeding and cautions with concurrent antiplatelet and anticoagulant drugs.” (same post)

And he’s upfront about the limits:

“No therapeutic claims can be made since large, prospective, double-blind randomized, placebo-controlled trials have not been completed on any of the compounds mentioned in this paper.” (The Focal Points, Aug 2023)

Before you try it

As Dr. McCullough notes, the main caution is bleeding. If you take blood thinners or aspirin, or you have surgery coming up, talk to your doctor or pharmacist first. It’s also worth checking before you combine it with bromelain or curcumin.

What to look for in a bottle

The activity listed in FU (fibrinolytic units), not just milligrams, plus a third-party testing seal and a seller you can verify.